Arestin®
Periodontal disease is a serious infection under your gumline.
ARESTIN® (minocycline hydrochloride) is an antibiotic that kills the bacteria that cause the infection.
- It is placed directly in the infected areas, or ”pockets,” in your gums.
- It may be placed right after scaling and root planing or when scaling and root planing is incorporated into a periodontal maintenance appointment. Recall that scaling and root planing is the dental procedure that disrupts stubborn plaque and bacteria below your gumline, where brushing and flossing can’t reach.
- It is a site-specific treatment, so it is not the type of treatment to be considered when the periodontal disease is generalized. Generalized cases may be best treated with an oral antibiotic instead of a site specific one.
- It starts working quickly, right at the source of infection, and keeps fighting bacteria long after you leave the dental office. 1,2
- It fights infection and inflammation for 30 days,2 and provides significantly better results than scaling and root planning alone for up to 90 days.3
- It is 60 percent effective after three tries, while most of our other treatment options have success rates of 95 percent.
1. Oringer RJ, Al-Shammari KF, Aldredge WA, et al. Effect of locally administered minocycline microspheres on markers of bone resorption. J Periodontol 2002;73:835-842.
2. Goodson JM, Gunsollwy JC, Grossi SG, et al. Minocycline HCl microspheres reduce red-complex bacteria in periodontal disease therapy. J Periodontol 2007;78(8):1568-1579.
3. Williams RC, Paquette DW, Offenbacher S, et al. Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial. J Periodontol 2001;72:1535-1544.